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Target intelligence / Profile preview
HIG1 domain family member 2B (HIGD2B)
- Target
- HIGD2B
- Molecular classification
- Other (annotated as a member of the hypoxia inducible gene domain (HIGD) family, closely related to mitochondrial membrane proteins)
01
Overview
HIG1 domain family member 2B (HIGD2B) is annotated as a member of the HIGD family based on sequence similarity, but there is limited to no published experimental evidence supporting its protein-coding status or biological function. It may correspond to a pseudogene or represent a gene prediction artifact, as reflected by its alias "putative HIG1 domain family member 2B" and "HIG1 hypoxia inducible domain family, member 2B (pseudogene)". No evidence currently supports its role as a therapeutic target, as a receptor, enzyme, or transporter, or its involvement in any established signaling pathways or diseases. In contrast, family members such as HIGD1A have clearly described roles in mitochondrial biology and stress response, but this cannot be inferred to HIGD2B without direct evidence.
- Other names
- HIGD2BHIGD2BPputative HIG1 domain family member 2BHIG1 hypoxia inducible domain family, member 2B (pseudogene)
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