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Target intelligence / Profile preview
HIG1 hypoxia inducible domain family member 1A pseudogene 18 (HIGD1AP18)
- Target
- HIGD1AP18
- Molecular classification
- Other (Pseudogene)
01
Overview
HIG1 hypoxia inducible domain family member 1A pseudogene 18 (HIGD1AP18) is a human pseudogene located on chromosome 8 that does not encode a functional protein product. It is related by sequence to the functional HIGD1A gene, which regulates mitochondrial homeostasis and cellular survival under stress, but HIGD1AP18 itself is not known to have biological or therapeutic significance[6][7][8]. This entry is specifically a pseudogene and should not be confused with HIG1 hypoxia inducible domain family member 1A (HIGD1A), a functionally relevant mitochondrial protein and potential therapeutic target in hypoxia-related, inflammatory, and neurodegenerative diseases[3][5][10]. HIGD1AP18 is listed in gene databases as a pseudogene and lacks protein-coding or known regulatory function[7][6][8].
- Other names
- HIGD1AP18
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