HIG1 hypoxia inducible domain family member 1A pseudogene 5 (HIGD1AP5)

HIG1 hypoxia inducible domain family member 1A pseudogene 5 (HIGD1AP5) is a pseudogene associated with the HIGD1A gene family, annotated in databases such as GeneCards and referenced as being a pseudogene and not protein coding. There is no evidence that HIGD1AP5 encodes a functional receptor, enzyme, transporter, or other typical drug target, nor is there evidence for it being a therapeutic target, involved in major biological functions, or relevant for disease, biomarker discovery, or drug interaction studies. Confusion can arise with the protein-coding gene HIGD1A, which is involved in mitochondrial function and stress response, but HIGD1AP5 itself is a non-functional genomic locus, not an active biological target[6][4][1]. Note: HIGD1AP5 refers specifically to the pseudogene. HIGD1A (sometimes confused variant) is a functional mitochondrial protein involved in hypoxia response and cell survival. Any therapeutic or biological targeting information relates to HIGD1A, not to the pseudogene HIGD1AP5[3][7][6]. If you intended information about the functional protein, you should refer to "HIG1 hypoxia inducible domain family member 1A" (HIGD1A), not HIGD1AP5.