HIG1 hypoxia inducible domain family member 2A (HIGD2A)

The entry "HIGD2A pseudogene 2" most likely denotes a pseudogene related to the functional gene HIGD2A. The protein encoded by HIGD2A (HIG1 hypoxia inducible domain family member 2A) is an inner mitochondrial membrane protein proposed to be a subunit of cytochrome c oxidase (complex IV), which is a terminal enzyme in the mitochondrial respiratory chain and a functional ortholog of yeast Rcf1. HIGD2A is involved in the assembly of mitochondrial respiratory complexes and supercomplexes, is regulated by stress (e.g., hypoxia, oxidative conditions), and may affect cancer cell survival and mitochondrial function[1][2][3]. "HIGD2A pseudogene 2" itself does not code for a characterized target or functional protein, is not a therapeutic target, and most databases do not provide structured drug or biomarker information for it, indicating likely misidentification or mislabeling in the query. Key clarification: - "HIGD2A pseudogene 2" is not a functional molecule or recognized therapeutic target. - If information about the functional mitochondrial protein is desired, use "HIG1 hypoxia inducible domain family member 2A" (HIGD2A)[3]. - For the pseudogene specifically, most scientific sources provide no biological or disease role, functional information, or therapeutic targeting data. - If your intent is to capture the canonical mitochondrial respiratory chain protein, use HIGD2A rather than the pseudogene.

Other names

HIG2AHIGD2A pseudogene 2