HIGD2A pseudogene 1 (HIGD2AP1)

HIGD2A pseudogene 1 (HIGD2AP1) is a non-protein-coding genomic element located on human chromosome 2[9]. It is classified as a pseudogene of the HIG1 hypoxia inducible domain family member 2A gene (HIGD2A)[3][9]. Unlike the functional HIGD2A gene, which encodes an inner mitochondrial membrane protein involved in the assembly and function of respiratory supercomplexes (cytochrome c oxidase complex IV)[5], HIGD2AP1 does not produce a functional protein product and has no reported biological or therapeutic roles[9]. There are no disease associations, biomarkers, or drug interactions known for HIGD2AP1. This entry should not be considered a valid therapeutic target. If detailed information about the protein-coding gene HIGD2A is needed, that should be requested separately, as HIGD2A itself is involved in mitochondrial respiratory chain activity and hypoxia-response[5][4].

Other names

HIG1 hypoxia inducible domain family member 2A pseudogeneHIGD2AP1