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High density lipoprotein binding protein pseudogene

Molecular classification: Pseudogene

Overview

High density lipoprotein binding protein pseudogene" (ENSG00000229911) refers to a non-functional genomic locus that has high sequence similarity to the gene for high density lipoprotein binding protein (HDLBP) but does not produce a functional protein. Pseudogenes arise from gene duplication or retrotransposition events and contain disabling mutations, such as frameshifts or premature stop codons, that prevent expression of a full-length, active protein. Pseudogenes do not serve as direct therapeutic targets, though in some contexts, their sequences or RNA products may influence the regulation of related functional genes[3].

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