Target intelligence / Profile preview

High mobility group box 1 pseudogene 11 (HMGB1P11)

Target
HMGB1P11
Molecular classification
Other (pseudogene; not a receptor, enzyme, transporter, transcription factor, ion channel, etc.)
01

Overview

High mobility group box 1 pseudogene 11 (HMGB1P11) is a human pseudogene related to the HMGB1 gene, which encodes a DNA-binding protein involved in chromatin structure, transcription regulation, DNA repair, and immune signaling[4][1][2][3][5]. However, as a pseudogene, HMGB1P11 does not produce a functional protein, has no described biological activity, and is not considered a therapeutic target. Literature on HMGB1P11 specifically is nearly absent, and the functional HMGB1 protein (not HMGB1P11) is the relevant molecule in molecular biology, therapeutic research, and disease contexts. If you were searching for information on the canonical functional protein, you should refer to **High mobility group box 1 protein (HMGB1)**, which is a DNA-binding architectural protein involved in transcription, DNA repair, cell death, inflammation, and acts as a damage-associated molecular pattern (DAMP) molecule in extracellular signaling[4][1][2][3][5]. HMGB1 is considered a drug target in diseases such as cancer, inflammation, and infection, but HMGB1P11 does not have these properties. Summary: HMGB1P11 is a pseudogene, not a functional protein or therapeutic target. Information related to receptors, drug interactions, disease roles, or molecular function does not apply. For molecular or therapeutic details, refer to HMGB1, not HMGB1P11[4][1][2][3][5].

Other names
HMGB1P11HMGB1L11high-mobility group box 1-like 11

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