High mobility group box 1 pseudogene 15 (HMGB1P15)

HMGB1P15 is a **pseudogene** in humans that is homologous to the high mobility group box 1 (HMGB1) family but does not encode a functional protein[1]. Pseudogenes are genomic DNA sequences similar to regular genes but have accumulated mutations that prevent them from producing functional products[9]. While some pseudogenes have been shown to have regulatory effects or limited function, most—including HMGB1P15—are considered non-functional and do not act as drug or biomarker targets. HMGB1P15 is cataloged in gene databases as a pseudogene and is not implicated in any validated physiological or pathological processes[1]. **Summary:** HMGB1P15 is not a druggable or functional target but a non-functional DNA sequence categorized as a pseudogene, with no evidence of being a therapeutic target, molecular marker, or causative agent in disease[1][9]. If you are seeking information about the **functional high mobility group box 1 protein (HMGB1)**, which is actively researched as a damage-associated molecular pattern and has roles in inflammation and cancer, that is a different molecule than HMGB1P15.

None known for this pseudogene