High mobility group box 1 pseudogene 23 (HMGB1P23)

High mobility group box 1 pseudogene 23 (HMGB1P23) is a processed pseudogene of the HMGB1 gene in humans[1][3]. Pseudogenes are DNA sequences that resemble functional genes but typically lack the ability to encode functional proteins due to mutations or lack of necessary regulatory elements. While some pseudogenes are transcribed and can act as regulatory non-coding RNAs (for example, by acting as microRNA sponges or competitive endogenous RNAs affecting the expression of parental or related genes), there is no direct evidence or functional annotation indicating that HMGB1P23 is transcribed or plays any functional biological or pathological role[3][4]. It is not considered a member of major molecular classes such as receptors, enzymes, ion channels, or transporters. Pseudogenes are generally not considered direct drug targets or biomarkers unless specifically demonstrated in scientific studies, and there are no drugs or mechanisms of action associated with HMGB1P23. If a therapeutic or experimental target in your context must be functionally expressed and play an active molecular role (e.g., as a receptor or enzyme), HMGB1P23 does **not** meet this definition. It is correctly annotated, but not a recognized biological or therapeutic target[1][3].

Other names

HMGB1P23