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High mobility group box 1 pseudogene 45 (HMGB1P45)

Target: HMGB1P45
Molecular classification: Other (Pseudogene)

Overview

HMGB1P45 is a human pseudogene—a disabled genetic copy of the functional HMGB1 gene. Unlike HMGB1, which encodes a nuclear non-histone protein involved in DNA organization, transcription regulation, and inflammatory signaling[1][3][5][7], HMGB1P45 does not produce a functional protein and has no established biological or disease-related activity. Pseudogenes like HMGB1P45 may have evolutionary relevance but are generally considered non-coding, and current evidence does not support any functional role in cell biology or disease pathways[2][4][6].

Other names: HMGB1 pseudogene 45HMGB1P45

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