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High mobility group box 1 pseudogene 48 (HMGB1P48) is a human pseudogene, meaning it is a non-functional copy of the high mobility group box 1 (HMGB1) gene[1][2][4]. Pseudogenes are typically considered "genomic fossils" and, unlike their protein-coding parent genes, do not encode proteins[2][3]. While some pseudogenes have been shown to play regulatory roles through their RNA transcripts in gene expression or disease, there is currently no evidence that HMGB1P48 acts as a receptor, enzyme, or other molecular target, nor is there known involvement in any disease or therapeutic process[2][3]. Therefore, HMGB1P48 is not recognized as a therapeutic target or biomarker and does not have known aliases, drug interactions, or associated safety concerns.
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