Target intelligence / Profile preview

High mobility group box 3 pseudogene 1 (HMGB3P1)

Target
HMGB3P1
Molecular classification
Other (Pseudogene)
01

Overview

High mobility group box 3 pseudogene 1 (HMGB3P1) is a pseudogene related to the high mobility group box protein family, located in humans and also referenced as HMG4L, HMGB3L1, or dJ18C9.3[1][3][5][6]. As a pseudogene, HMGB3P1 is considered a non-functional genetic remnant; it shares sequence similarity with functional genes but does not encode a functional protein due to the accumulation of disabling mutations or regulatory silencing[2]. There is no evidence that HMGB3P1 serves as a therapeutic target (such as a receptor, enzyme, transporter, or transcription factor), nor is it known to directly participate in canonical biological processes, disease mechanisms, or drug–target interactions. While some pseudogenes can have regulatory roles at the RNA level, there are no established data or therapeutic implications for HMGB3P1 in these contexts[2][5].

Other names
HMG4LHMGB3L1dJ18C9.3[1][3][5]
02

Biological functions

Other (No known biological function as a protein; may have non-coding or regulatory RNA roles, but not established as canonical protein function)
03

Disease associations

Other (Not established as a direct disease contributor; potentially implicated via regulatory RNA pathways, but data is lacking)

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