Target intelligence / Profile preview

High mobility group box 3 pseudogene 15 (HMGB3P15)

Target
HMGB3P15
Molecular classification
Other, pseudogene, noncoding RNA
01

Overview

High mobility group box 3 pseudogene 15 (HMGB3P15) is a pseudogene in the human genome[1]. Pseudogenes are DNA sequences similar to functional genes but contain mutations or arrangements that prevent them from encoding a functional protein[3]. While some pseudogenes are transcribed into noncoding RNAs capable of influencing the regulation of their parental gene or other cellular processes, most—including HMGB3P15—have not been shown to have a specific biological function or role as a drug target[1][3]. Pseudogenes in general may act as microRNA decoys or participate in noncoding RNA networks, occasionally being implicated in the regulation of diseases such as cancer[2][3], but there is no direct evidence of such a role for HMGB3P15.

Other names
HMGB3P15
02

Biological functions

Possible regulation of gene expression through noncoding RNA pathways
03

Disease associations

Pseudogenes have been implicated in cancer and other diseases as regulatory elements, but no direct disease association is documented for HMGB3P15

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