High mobility group box 3 pseudogene 19 (HMGB3P19)

High mobility group box 3 pseudogene 19 (HMGB3P19) is a human pseudogene, meaning it is a segment of DNA that bears high sequence similarity to the coding gene HMGB3, but due to accumulated mutations, it cannot encode a functional protein. Pseudogenes like HMGB3P19 typically arise from gene duplication or retrotransposition events; they lack the regulatory elements or harbor mutations that prevent transcription or translation, and therefore do not have protein-coding capacity or direct biological functions. Although some pseudogenes have regulatory roles or appear as disease biomarkers, there is no evidence that HMGB3P19 is implicated in disease or is considered a drug target[1][3][7].

Other names

high mobility group protein B3-like protein-like pseudogene