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High mobility group box 3 pseudogene 2 (HMGB3P2)

Target
HMGB3P2
Molecular classification
Other (classified as a pseudogene within the high mobility group box DNA-binding domain gene family)
01

Overview

HMGB3P2 (High mobility group box 3 pseudogene 2, dJ550H1.1) is a human pseudogene related to the high mobility group box 3 (HMGB3) gene family. Pseudogenes are segments of DNA that resemble functional genes but typically lack protein-coding ability due to mutations, deletions, or other genomic alterations. HMGB3P2 shares sequence similarity with HMGB3 but does not produce a functional protein product [1][4][7]. Pseudogenes like HMGB3P2 can sometimes exert biological effects by influencing regulatory networks, such as acting as competitive endogenous RNAs or miRNA decoys, but no specific biological or disease relevance has been attributed to HMGB3P2 itself[2][6]. HMGB3P2 is not considered a conventional therapeutic target and does not interact with approved drugs. It is primarily annotated as a genomic element in reference databases and research literature.

Other names
dJ550H1.1HMG4L2HMGB3L2
02

Biological functions

May participate in gene regulation through non-coding RNA mechanisms such as acting as miRNA decoys or influencing mRNA stability by sequence similarity to its parent gene (general pseudogene functions)
03

Disease associations

Other (no direct disease association; pseudogenes sometimes implicated via regulatory noncoding RNA effects, but no reported link for HMGB3P2 specifically)

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