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High mobility group box 3 pseudogene 22 (HMGB3P22)

Target
HMGB3P22
Molecular classification
Other
01

Overview

High mobility group box 3 pseudogene 22 (HMGB3P22) is a human DNA segment classified as a pseudogene, meaning it resembles the functional high mobility group box 3 (HMGB3) gene but has accumulated mutations that prevent it from encoding a functional protein[2][3]. Pseudogenes like HMGB3P22 are not typically translated into protein and do not function as receptors, enzymes, or other conventional drug targets. While some pseudogenes have been implicated in regulatory roles—such as acting as microRNA sponges, influencing the expression of related genes, or producing regulatory noncoding RNAs—such functions have not been specifically established for HMGB3P22. This pseudogene is annotated in genomic databases for reference but is not a valid therapeutic target and does not interact with known drugs[1][2][3].

Other names
HMGB3P22
02

Biological functions

Can act as a source of regulatory noncoding RNA in rare casesMay participate in genetic regulation via RNA interference or as a microRNA decoy in very specific contexts, though this has not been demonstrated for HMGB3P22 specifically
03

Disease associations

Other

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