Target intelligence / Profile preview

High mobility group box 3 pseudogene 29 (HMGB3P29)

Target
HMGB3P29
Molecular classification
Other (Pseudogene)
01

Overview

High mobility group box 3 pseudogene 29 (HMGB3P29) is classified as a **pseudogene**, which means it is a non-functional DNA sequence related to the HMGB3 gene but is not believed to encode a functional protein[5]. Pseudogenes arise from duplication or mutation of protein-coding genes and generally accumulate mutations that prevent protein production[6]. While *some* human pseudogenes are transcribed into non-coding RNAs with potential regulatory functions (e.g., acting as competing endogenous RNAs or miRNA decoys[2][4]), there is no specific evidence that HMGB3P29 itself has such a role. Pseudogenes like HMGB3P29 are **not considered therapeutic targets** (receptors, enzymes, etc.), and there is no information about drugs, biomarkers, or safety considerations relevant to this pseudogene[5]. The entry is **"incorrect as a target"** in the sense that pseudogenes are not established pharmacological or biological targets, and HMGB3P29 is not listed as a protein, receptor, or enzyme with biological activity or disease causality[5][6].

Other names
High mobility group box 3 pseudogene 29HMGB3P29ENSG00000254503
02

Biological functions

Other (No protein product; potential regulatory noncoding RNA function in principle, but no specific function described for HMGB3P29)
03

Disease associations

Other (No direct evidence; some pseudogenes are implicated as regulators in disease, but not this one specifically)

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