High mobility group nucleosomal binding domain 2 pseudogene 47 (HMGN2P47)

HMGN2P47 is a noncoding pseudogene in humans, formally identified as high mobility group nucleosomal binding domain 2 pseudogene 47. As a pseudogene, HMGN2P47 shares high sequence homology with the functional HMGN2 gene, which encodes a member of the high-mobility group chromosomal protein family involved in chromatin structure and regulation. However, HMGN2P47 itself does not code for a functional protein product and is not involved in normal or pathogenic biological pathways as an active molecule[3][5][7]. While some pseudogenes can exert regulatory effects (e.g., acting as competitive endogenous RNAs or miRNA decoys), there is no specific evidence in the literature for such a role for HMGN2P47[2][4]. It is not considered a therapeutic target, is not associated with any known drugs, and does not serve as a biomarker or have notable safety considerations.

Other names

HMGN2 pseudogene 47