Highly divergent homeobox (HDX)

Highly divergent homeobox (HDX) is a protein-coding gene located on the X chromosome (Xq21.1) that encodes a predicted DNA-binding transcription factor believed to function primarily in the regulation of gene transcription mediated by RNA polymerase II. It is predominantly associated with chromatin and exhibits sequence-specific regulatory activity. Disease associations include autism spectrum disorder and Fraser syndrome 1. There is currently no evidence that HDX is a direct therapeutic target or has described interacting drugs, mechanisms of action, biomarker roles, or specific safety concerns[1][2][4][6].

Other names

CXorf43D030011N01RikFLJ30678