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Hippocampus abundant transcript 1 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

Hippocampus abundant transcript 1 pseudogene (ENSG00000254590) is a pseudogene, meaning it is a genomic sequence similar to a functional gene but does not encode a functional protein due to disruptive mutations such as premature stop codons or frameshifts[1][6][7]. Pseudogenes are typically remnants of once-functional genes, and may not produce any functional RNA or protein products; however, some pseudogenes in general can have regulatory functions as non-coding RNAs, including roles as decoys for microRNAs or as sources of small interfering RNA, affecting gene expression. For this specific pseudogene, no evidence supports a protein-coding function, a specific regulatory role, therapeutic targeting, or disease association[1][6]. It is not a therapeutic target or receptor, and its inclusion in target lists is likely due to a misunderstanding or database filtering artifact. Key points: - This entry refers to a noncoding pseudogene, not a functional protein, receptor, or druggable target[1][6][7]. - Pseudogenes in general may rarely play regulatory or biomarker roles, but there is no specific evidence for such a function here[3][6]. - It is marked as incorrect for use as a canonical drug target or receptor.

Other names
HIAT1 pseudogeneENSG00000254590
02

Biological functions

Other (no known biological function as a protein-coding gene; general pseudogene functions include regulatory RNA roles such as potential RNA interference or microRNA decoy activity, but no such function is established for this specific pseudogene)
03

Disease associations

Other (no established disease association; in general, pseudogenes may have regulatory roles in diseases, but none are described for this entry)

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