Histone deacetylase class IV enzymes (HDAC class IV)

Histone deacetylase class IV enzymes are part of a larger family of enzymes that remove acetyl groups from lysine residues on histones, thereby regulating chromatin structure and gene expression. They play roles in various cellular processes, including cell cycle regulation and differentiation, and are implicated in diseases such as cancer and metabolic disorders. However, it's worth noting that the classification of HDACs typically includes classes I, II, III, and IV, with class IV not being a commonly recognized category in the literature. The most commonly discussed classes are I, II, and III, with class II being further divided into IIa and IIb. Class IV might be a misunderstanding or misclassification, as the typical classification does not include a class IV. Given the confusion around "class IV," it might be more accurate to discuss HDACs in general or focus on specific classes like HDAC4, which is a class II HDAC.

Other names

Histone deacetylase class IVHDAC class IV

Inhibition of histone deacetylation, leading to increased acetylation of histones and altered gene expression.