Histone H2B pseudogene 6 (H2BP6)

Histone H2B pseudogene 6 (H2BP6) is a member of the human histone cluster 1, with sequence similarity to the core histone H2B gene family, but classified as a **pseudogene** and does not code for a functional protein[2][4]. Histone pseudogenes arise from gene duplication and mutation events, sometimes retaining regulatory or noncoding RNA functions but typically not translated into protein or participating in canonical histone/chromatin biology[3][4]. While functional histone H2B proteins are critical for chromatin structure and regulation of transcription, DNA replication, and repair[1][4], pseudogenes like H2BP6 do not participate directly in these processes, and there is no evidence for direct involvement in disease, drug interaction, or serving as biomarkers.

Other names

HIST1H2BPS3HIST1H2B pseudogene 3histone cluster 1 H2B pseudogene 3histone cluster 1, H2b, pseudogene 3H2BP6