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HLA-B associated transcript 2 pseudogene (No canonical abbreviation; "BAT2P" and "HLA-B associated transcript 2 pseudogene" are used, but ENSG00000233383 is not the coding gene for PRRC2A/BAT2, which may sometimes be referred to as "HLA-B associated transcript 2")

Target
No canonical abbreviation; "BAT2P" and "HLA-B associated transcript 2 pseudogene" are used, but ENSG00000233383 is not the coding gene for PRRC2A/BAT2, which may sometimes be referred to as "HLA-B associated transcript 2"
Molecular classification
Other, Pseudogene (Non-coding DNA with high sequence similarity to functional genes, but generally non-functional and not translated into protein)
01

Overview

HLA-B associated transcript 2 pseudogene (ENSG00000233383) is a genomic locus in the human chromosome 6 major histocompatibility complex (MHC) region that shares high sequence similarity with HLA-B associated transcript 2 (BAT2/PRRC2A), but lacks protein-coding capacity and is considered a pseudogene. It is not recognized as a functional protein-coding gene, receptor, or enzyme, and is generally excluded from lists of therapeutic targets. While some pseudogenes may have regulatory roles or expression in certain tissues or cancers, there is no specific or canonical biological, disease, or pharmaceutical role for this pseudogene. If you were searching for "HLA-B associated transcript 2" as a protein-coding therapeutic target, that would be PRRC2A (BAT2), encoded by ENSG00000204469. PRRC2A is a protein-coding gene and is sometimes confused due to aliasing, but ENSG00000233383 is not PRRC2A and is not a protein-coding target. If you need information about PRRC2A (BAT2), specify "PRRC2A" or ENSG00000204469.

Other names
HLA-B associated transcript 2 pseudogeneENSG00000233383
02

Mechanism of action

None, as this pseudogene is not a drug target.

03

Biological functions

Other (pseudogenes generally do not encode functional proteins and may have limited biological functions, though some pseudogene RNAs are reported to be expressed and may have minor, poorly understood regulatory roles in certain cancers and tissues)
04

Disease associations

OtherThere is no specific disease association or established disease role for HLA-B associated transcript 2 pseudogene. Some pseudogenes are deregulated in cancer, but this particular pseudogene is not reported among major deregulated pseudogenes in cancer datasets
05

Safety considerations

None known, as this is not a therapeutic target.
06

Interacting drugs

None. No drugs are known to interact with this pseudogene.
07

Biomarkers

None established for patient selection or efficacy monitoring.

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