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Target intelligence / Profile preview
HLA complex group 4 pseudogene (HCG4P)
- Target
- HCG4P
- Molecular classification
- Pseudogene, Non-coding RNA, Major histocompatibility complex (MHC) region gene
01
Overview
HLA complex group 4 pseudogene (ENSG00000271581) is a non-coding DNA segment located in the human major histocompatibility complex (MHC)/HLA locus on chromosome 6. It does not encode a protein or exert a known biological function and is considered a nonfunctional genomic remnant—possibly a byproduct of evolutionary gene duplication within the highly polymorphic HLA region. While some HLA pseudogenes can produce non-coding RNAs, there is no evidence this particular pseudogene acts as a functional regulatory RNA. It does not participate in antigen presentation or immune signaling, and it is not used as a diagnostic or therapeutic marker. This is not a conventional molecular target—it is classified as a pseudogene in the HLA region and should not be annotated as a receptor, enzyme, transporter, or direct drug target.
- Other names
- HLA complex group 4 pseudogeneHCG4PENSG00000271581HCG4B
02
Mechanism of action
None
03
Biological functions
No known protein-coding functionPossible non-coding regulatory RNA (unconfirmed)
04
Disease associations
No direct role attributedNo direct role in disease; associations may be due to linkage disequilibrium with functional HLA genes involved in autoimmunity, infection, and transplantation, but the pseudogene itself is not causal
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