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HLA complex group 9 pseudogene 5 (HCG9P5)

Target: HCG9P5
Molecular classification: Pseudogene, Non-coding RNA

Overview

HLA complex group 9 pseudogene 5 (HCG9P5) is a human pseudogene within the major histocompatibility complex (MHC), also annotated as HCGIX-5 or dJ377H14.6[1][2][4]. It does not produce a functional protein, and its precise biological role, if any, remains unknown; some studies have examined the methylation status of the broader HLA complex group 9 region in psychiatric disease, but HCG9P5 itself is not established as a functional or therapeutic target[1][2][3][4][5]. It is not used in drug targeting, biomarker development, or clinical safety evaluation.

Other names: HCGIX-5dJ377H14.6

Biological functions

Other (no confirmed biological function; related HLA/MIC genes have immune roles, but HCG9P5 itself is likely non-functional)

Disease associations

Other (no established direct disease role; methylation changes in the extended HCG9 region—not specifically HCG9P5—have been studied in psychiatric conditions such as bipolar disorder and schizophrenia)

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