Target intelligence / Profile preview

Homocysteine (Hcy)

Target
Hcy
Molecular classification
Amino Acid, Metabolite, Intermediate
01

Overview

Homocysteine is a non-proteinogenic, sulfur-containing α-amino acid found in the blood. It is an intermediate in methionine and cysteine metabolism. Elevated levels are associated with increased risk for cardiovascular diseases and other health issues.

02

Mechanism of action

N/A - Homocysteine itself is not directly targeted by drugs but its metabolism is influenced by vitamin supplementation.

03

Biological functions

Amino acid metabolismIntermediate in methionine and cysteine metabolismProtein modification
04

Disease associations

Cardiovascular diseaseVenous thrombosisNeural tube defectsHyperhomocysteinemiaHomocystinuria
05

Safety considerations

Elevated homocysteine levels associated with increased risk of cardiovascular diseases and other health problems
06

Interacting drugs

Vitamin B6

2 more in the full profile.

07

Biomarkers

Plasma homocysteine levels

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