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Host cell migration is the orchestrated movement of cells within an organism, essential for tissue formation during development, wound repair, immune surveillance, and angiogenesis[1][5]. It is driven by cytoskeletal remodeling, cell–extracellular matrix interactions, and a range of signaling events. The process is tightly regulated and involves a complex interplay of receptors (such as chemokine or growth factor receptors), signaling proteins (like Rho GTPases), and the extracellular matrix[1][3][5]. While modulation of migration is a therapeutic goal in some diseases (notably cancer metastasis and immune disorders), "host cell migration" itself is not a specific molecular target but a process regulated by many discrete molecular entities. Note: If the request is for a specific molecular regulator or receptor governing host cell migration (e.g., "C-X-C chemokine receptor type 4", "Integrin beta-1", "RhoA GTPase"), please specify for more precise, target-level data.
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