Target intelligence / Profile preview

Host cell migration

Molecular classification
Other
01

Overview

Host cell migration is the orchestrated movement of cells within an organism, essential for tissue formation during development, wound repair, immune surveillance, and angiogenesis[1][5]. It is driven by cytoskeletal remodeling, cell–extracellular matrix interactions, and a range of signaling events. The process is tightly regulated and involves a complex interplay of receptors (such as chemokine or growth factor receptors), signaling proteins (like Rho GTPases), and the extracellular matrix[1][3][5]. While modulation of migration is a therapeutic goal in some diseases (notably cancer metastasis and immune disorders), "host cell migration" itself is not a specific molecular target but a process regulated by many discrete molecular entities. Note: If the request is for a specific molecular regulator or receptor governing host cell migration (e.g., "C-X-C chemokine receptor type 4", "Integrin beta-1", "RhoA GTPase"), please specify for more precise, target-level data.

Other names
Cell migrationCellular migrationMigratory process of host cell
02

Biological functions

Cell motilityTissue repairEmbryonic developmentImmune responseAngiogenesisWound healing
03

Disease associations

Cancer (metastasis)InflammationImmune deficiencyChronic woundsFibrosisVascular disease

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