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Host cell proteins present in the viral envelope
- Molecular classification
- Integral membrane proteins, Receptors, Adhesion molecules, MHC molecules, Tetraspanins, Transporters
01
Overview
Host cell proteins present in the viral envelope refer to cellular proteins that are incorporated into the lipid bilayer of enveloped viruses during their assembly and budding from host cells. The viral envelope itself is primarily derived from portions of the host cell membrane, such as the plasma membrane or internal membranes (e.g., endoplasmic reticulum, Golgi apparatus), and thus can contain both host-derived lipids and proteins alongside virus-encoded glycoproteins. These incorporated cellular components play roles beyond structural support—affecting how virions interact with new target cells and evade immune responses.
02
Biological functions
Immune evasionCellular tropismModulation of virion interaction with target cells
03
Disease associations
Viral pathogenesisInfection
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