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Host Defense Response
- Molecular classification
- Immune system, Innate immunity, Adaptive immunity, Physical barriers, Chemical barriers
01
Overview
The host defense response refers to the collective biological mechanisms by which an organism protects itself from infectious agents. It encompasses both innate and adaptive immunity, physical and chemical barriers, and the contribution of the normal microbiota. Failures or dysregulation of these responses can lead to infection, immunodeficiency, autoimmunity, or allergy.
02
Biological functions
Immune responsePathogen recognitionInflammationTissue repairHomeostasis maintenanceAntimicrobial activity
03
Disease associations
InfectionImmunodeficiencyAutoimmunityAllergyCancer
04
Safety considerations
ImmunosuppressionCytokine stormAutoimmunityAllergic reactions
05
Interacting drugs
Immunosuppressants
5 more in the full profile.
06
Biomarkers
Cytokine levelsAntibody titersImmune cell countsExpression of pattern recognition receptors
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