Host immune modulation

"Host immune modulation" refers to the regulatory adjustment, either natural or therapeutic, of the immune system's response to achieve balance (homeostasis) or a specific desired effect. It covers diverse mechanisms including upregulation or suppression of immune cell activity, cytokine production, or immune signaling pathways in order to treat conditions like autoimmune diseases, infection, or cancer. This is not a defined molecule, receptor, or protein, but a general strategy or field of intervention[1][3]. "Host immune modulation" is a term referring to complex adaptive and innate immune mechanisms and pathways, but is not itself a molecular target; thus, it should not be treated as one for structured databases[1][3].

Other names

ImmunomodulationImmune modulationHost immune response modulation

Inhibition or enhancement of immune cell activity, cytokine modulation, induction of regulatory T cells, blockade of co-stimulatory or inhibitory pathways, antibody- or cell-mediated cytotoxicity