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HOTAIRM1-HOXA-AS2 readthrough transcript (HOTAIRM1-HOXA-AS2)
- Target
- HOTAIRM1-HOXA-AS2
- Molecular classification
- Other
01
Overview
The HOTAIRM1-HOXA-AS2 readthrough transcript is a long non-coding RNA resulting from read-through transcription between two lncRNAs, HOTAIRM1 and HOXA-AS2, within the human HOXA gene cluster. While its components (HOTAIRM1 and HOXA-AS2) have individually documented roles in regulation of chromatin structure, gene expression, cell differentiation, and apoptosis (particularly in hematologic contexts), the specific biological role of the readthrough transcript itself has not been characterized or linked to therapeutic targeting or clinical biomarker use[1][3]. Readthrough transcripts are primarily noted in genomic databases and may reflect cellular transcriptional complexity rather than distinct biological entities.
- Other names
- HOTAIRM1-HOXA-AS2 readthrough transcriptENSG00000293629
02
Biological functions
Regulation of chromatin structureCell proliferation and apoptosisPossible regulation of gene expression
03
Disease associations
CancerCell differentiation disorders
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