Dermatophagoides pteronyssinus allergen

Dermatophagoides pteronyssinus is a house dust mite whose allergens are a major cause of allergic diseases. The primary allergens, Der p 1, Der p 2, and Der p 23, trigger IgE-mediated hypersensitivity reactions and can also activate innate immune pathways. Exposure to these allergens leads to symptoms like rhinitis, asthma, and eczema. Diagnosis involves skin-prick testing or measuring specific IgE levels. Treatment includes allergen avoidance, medications, and allergen immunotherapy.

Other names

House dust mite allergenD. pteronyssinus allergen

IgE crosslinking on mast cells and basophils, leading to histamine and mediator release; TLR4 activation (Der p 2)