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Target intelligence / Profile preview
HSD17B1 antisense RNA 1 (HSD17B1-AS1)
- Target
- HSD17B1-AS1
- Molecular classification
- Long non-coding RNA, lncRNA
01
Overview
HSD17B1 antisense RNA 1 (HSD17B1-AS1) is a long non-coding RNA transcribed antisense to the *HSD17B1* gene, which encodes the enzyme 17β-hydroxysteroid dehydrogenase type 1. Antisense RNAs like HSD17B1-AS1 are generally involved in regulatory functions, typically modulating the expression of their sense gene partner via transcriptional interference, mRNA stability, or epigenetic changes. There is no established role for HSD17B1-AS1 as a direct therapeutic target, nor is it well studied in the context of human disease or drug discovery, according to the results provided. Most research and clinical interest is currently focused on the enzymatic protein *HSD17B1*[1][4][7], rather than on its antisense non-coding transcript.
- Other names
- HSD17B1-AS1
02
Biological functions
Gene expression regulationModulation of mRNA stabilityTranscriptional interference
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