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Target intelligence / Profile preview
HSD17B12 pseudogene 1 (HSD17B12P1)
- Target
- HSD17B12P1
- Molecular classification
- Other (Pseudogene)
01
Overview
HSD17B12 pseudogene 1 (HSD17B12P1) is a pseudogene identified in the genome of certain mouse strains (notably BALB/c) but not in humans[1]. It is related to the active HSD17B12 gene, which encodes hydroxysteroid (17-beta) dehydrogenase 12, an enzyme critical for estrone-to-estradiol conversion and fatty acid elongation[2][3][5]. The pseudogene can encode variant peptides expressed in some mouse tumors but shows no evidence of functional importance or expression in normal physiology or human disease[1]. Because HSD17B12P1 is neither active in humans nor associated with drugs or therapeutics, it should not be considered a therapeutic target.
- Other names
- HSD17B12P1Hsd17b12 pseudogene
02
Biological functions
Other (no known biological function as a pseudogene in humans; limited expression in certain murine sarcomas[1])
03
Disease associations
Other (no established disease relevance in humans; rare laboratory findings in mouse tumor models[1])
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