HSPA5 pseudogene 1 (HSPA5P1)

HSPA5 pseudogene 1 (HSPA5P1) is a non-functional pseudogene related to the heat shock protein family A (Hsp70) member 5 gene (HSPA5/BiP/GRP78). Unlike the canonical HSPA5 gene, which encodes an endoplasmic reticulum chaperone with critical roles in protein folding, stress response, and disease processes (such as cancer and metabolic disease), HSPA5P1 does not produce a functional protein and is not considered a therapeutic target[3]. There are no established biological functions, disease associations, or drug interactions attributed to HSPA5P1. Any therapeutic or research relevance is related exclusively to the protein-coding HSPA5 gene and not the pseudogene HSPA5P1[3]. If you intended to inquire about the functional gene (HSPA5, also known as GRP78/BiP), please clarify, as HSPA5 is a major regulator of ER homeostasis and is an established therapeutic target in areas such as cancer and metabolic disease[1][2].

Other names

HSPA5 pseudogene 1heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) pseudogeneheat shock protein family A (Hsp70) member 5 pseudogeneHSPA5P1