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Human crystalline lens

Molecular classification
Other (tissue/organ, not a molecule or protein)
01

Overview

The human crystalline lens is a transparent, biconvex structure in the eye that focuses light onto the retina to enable clear vision. It is composed mainly of lens proteins called crystallins (α-, β-, and γ-crystallins) and specialized fiber cells that lack organelles to maintain optical clarity[2][4][3]. Over time, the lens can develop opacities (cataracts), leading to impaired vision that is often treated by surgical removal and replacement of the lens with a prosthetic intraocular lens (IOL) rather than by drugs. The term "human crystalline lens replacement" therefore refers to a surgical procedure, not to a molecular or drug target.

Other names
Crystalline lensLens of the eyeOcular lens
02

Biological functions

Light focusingMaintenance of ocular transparencyAccommodation (focusing at different distances)
03

Disease associations

CataractPresbyopiaLens opacitiesGenetic lens diseases
04

Safety considerations

Surgical complications (infection, posterior capsule opacification, intraocular lens dislocation)

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