Target intelligence / Profile preview

Human metapneumovirus (hMPV)

Target: hMPV
Molecular classification: Virus, RNA virus, Pneumoviridae

Overview

Human metapneumovirus (hMPV) is an enveloped, nonsegmented, negative-sense RNA virus belonging to the Pneumoviridae family. It is a common cause of upper and lower respiratory tract infections worldwide, particularly affecting young children, older adults, and immunocompromised individuals. Transmission occurs via respiratory droplets and direct contact. There is currently no specific antiviral treatment available, with management focused on supportive care.

Other names: hMPV

Mechanism of action

Supportive care (no specific antiviral treatment)

Biological functions

Host cell infectionReplicationRespiratory infection

Disease associations

Respiratory illnessPneumoniaBronchiolitisUpper respiratory tract infectionLower respiratory tract infection

Safety considerations

Severe disease in young children, older adults, and immunocompromised individualsExacerbation of underlying chronic lung conditions

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