Target intelligence / Profile preview

Human Papillomavirus L1 Major Capsid Protein (L1)

Target: L1
Molecular classification: Structural Protein, Capsid Protein

Overview

The human papillomavirus major capsid protein L1 is essential for forming infectious virus particles through its ability to self-assemble into stable structures that encapsulate viral DNA. Its structural features make it both a critical component of natural infection processes and an ideal target for vaccine development due to its strong immunogenic properties and capacity to induce protective antibody responses against multiple HPV types.

Other names: HPV L1L1 major capsid protein

Mechanism of action

Induction of neutralizing antibodies against HPV L1 protein, preventing viral entry and infection

Biological functions

Capsid AssemblyHost Cell AttachmentViral DNA EncapsulationImmunogen

Disease associations

InfectionCancer (Cervical, etc.)

Interacting drugs

HPV Vaccines (e.g., Gardasil, Cervarix)

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