Target intelligence / Profile preview

Human Papillomavirus Type 6 Major Capsid Protein (L1)

Molecular classification
Viral structural protein, Capsid protein
01

Overview

The major capsid protein L1 from human papillomavirus type 6 is essential for virus assembly and infectivity. Its ability to form highly immunogenic virus-like particles has been harnessed successfully for preventive vaccines against multiple clinically relevant HPV types including those causing genital warts and cancers. Its structure-function relationship—especially its capacity to mimic native virions—makes it a cornerstone target molecule both biologically and therapeutically.

Other names
Human papillomavirus type 6 L1 capsid protein antigenRecombinant human papillomavirus type 6 L1 proteinL1 protein, Human papillomavirus type 6 Vaccine
02

Mechanism of action

Induction of neutralizing antibodies through VLP presentation of L1 epitopes

03

Biological functions

Viral capsid formationGenome protectionVirus assemblyInfectivityImmunogen
04

Disease associations

InfectionGenital warts (HPV-6 related)
05

Interacting drugs

Gardasil (vaccine)

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