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Human papillomavirus type 68 (HPV68)

Target: HPV68
Molecular classification: Virus, Papillomavirus, Alphapapillomavirus 7

Overview

Human papillomavirus type 68 (HPV68) is a non-enveloped double-stranded DNA virus in the Papillomaviridae family, specifically Alphapapillomavirus 7 species, classified by L1 gene sequence similarity (≥70% species, <90% type). It is probably carcinogenic (IARC Group 2A), associated with cervical cancer (detected in ~0.8-2% of cases), particularly its ME180 subtype which confers cell immortalization; detection challenges exist with certain PCR assays like SPF10 or MY09-MY11. Variants include HPV68a and HPV68b, forming phylogenetic branches.

Other names: HPV-68Human papillomavirus 68HPV68aHPV68b

Biological functions

OncogenesisInfectionCell immortalization

Disease associations

Cervical cancerGenital warts

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