Target intelligence / Profile preview

Hydrogen Ion (H+)

Target
H+
Molecular classification
Ion, Cation
01

Overview

The hydrogen ion (H+) is a cation consisting of a single proton. It plays a crucial role in determining the acidity (pH) of solutions and is fundamental to acid-base chemistry. While often referred to as a proton, it exists predominantly in hydrated forms such as hydronium (H3O+) in aqueous solutions. The concentration of H+ ions is vital for various biological processes, and imbalances can contribute to numerous diseases.

Other names
ProtonHydronProtium ionDeuteronTriton
02

Mechanism of action

Acids donate H+; bases accept H+. PPIs inhibit H+/K+ ATPase.

03

Biological functions

pH regulationAcid-base catalysisProton gradient formationCharge carrier
04

Disease associations

AcidosisAlkalosisIschemic injuryInflammation
05

Safety considerations

Acid-base imbalanceTissue damage (acids/bases)Drug interactions affecting pH
06

Interacting drugs

Acids

4 more in the full profile.

07

Biomarkers

pHArterial blood gas (ABG)Serum bicarbonate

Beyond the preview

Go deeper on Hydrogen Ion (H+).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Hydrogen Ion (H+).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call