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Hydrogen Ion Concentration in Blood Plasma (None)
- Target
- None
- Molecular classification
- Physiological Parameter, Electrolyte Balance, Acid-Base Balance
01
Overview
Hydrogen ion concentration in blood plasma is a critical physiological parameter that determines the acidity or alkalinity (pH) of the blood. The pH scale, which is logarithmic and inversely proportional to hydrogen ion concentration, typically ranges from 7.35 to 7.45 in healthy individuals. Even minor deviations from this range can significantly disrupt cellular processes and enzymatic functions, potentially leading to severe health consequences. It is not a direct therapeutic target itself, but rather a measured physiological state. Interventions aim to correct underlying causes of imbalances affecting hydrogen ion concentration.
02
Mechanism of action
Modulation of acid-base balance through various mechanisms including buffering, renal excretion/reabsorption, and respiratory regulation.
03
Biological functions
Maintains acid-base homeostasisInfluences enzyme activityInfluences protein structureRegulates metabolic function
04
Disease associations
AcidosisAlkalosisMetabolic disordersRespiratory disordersRenal disorders
05
Safety considerations
Severe acidosisSevere alkalosisElectrolyte imbalancesCardiac arrhythmiasNeurological dysfunction
06
Interacting drugs
Bicarbonate
3 more in the full profile.
07
Biomarkers
Arterial blood pHPartial pressure of carbon dioxide (pCO2)Bicarbonate (HCO3-) levelsBase excess
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