Target intelligence / Profile preview

Hydrogen Sulfide Release (H2S Release)

Target
H2S Release
Molecular classification
Biological Process
01

Overview

Hydrogen sulfide release is a complex biological process involving the production, storage, and liberation of H₂S gas. This process relies on enzymes such as cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), and 3-mercaptopyruvate sulfurtransferase (3-MST), utilizing substrates like cysteine and methionine. H₂S acts as a signaling molecule with roles in neuromodulation, vasodilation, and redox signaling, and its dysregulation is implicated in various diseases.

Other names
H₂S ReleaseHydrogen sulfide biogenesisHydrogen sulfide production
02

Mechanism of action

N/A

03

Biological functions

NeuromodulationVasodilationCellular signalingRedox regulationGasotransmitter function
04

Disease associations

Neurodegenerative diseasesCardiovascular diseasesInflammationOxidative stress-related diseases
05

Safety considerations

High concentrations can be toxic, leading to respiratory irritation and neurological symptoms.

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