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Hydroxyacyl-CoA dehydrogenase pseudogene

Molecular classification
Other
01

Overview

Hydroxyacyl-CoA dehydrogenase pseudogene (ENSG00000261072) is a nonfunctional DNA sequence with high similarity to the hydroxyacyl-CoA dehydrogenase gene, a mitochondrial enzyme involved in the beta-oxidation of fatty acids. While the functional gene plays important metabolic and clinical roles, such as in fatty acid oxidation disorders, this pseudogene does not encode a protein and has no known direct role in biological function or disease. It is not considered a therapeutic target, nor does it have established utility in pharmacology or biomarker research[3][4][5]. Context and clarification: - If you are seeking information about the *functional* hydroxyacyl-CoA dehydrogenase, refer to the gene *HADH* (Ensembl: ENSG00000138796), which encodes an active enzyme with metabolic and clinical significance[1][5][6][7]. - The distinction is important: **pseudogenes** like ENSG00000261072 are generally excluded from drug target lists in pharmacology and biomedical research. If you require information on the functional enzyme instead, such as "Hydroxyacyl-CoA dehydrogenase" (HADH), please clarify.

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