Target intelligence / Profile preview

Hypochlorous Acid (HOCl)

Target: HOCl
Molecular classification: Oxidizing agent, Antimicrobial agent

Overview

Hypochlorous acid (HOCl) is a weak, unstable acid and a powerful oxidizing agent with broad-spectrum antimicrobial activity. It is produced by neutrophils as part of the immune response and is effective against bacteria, viruses, fungi, spores, and biofilms. It disrupts microbial cell membranes, damages DNA and proteins, and inhibits essential enzymes. HOCl is used in wound care, ophthalmology, and dermatology due to its efficacy and safety profile.

Mechanism of action

Oxidizes and disrupts microbial cell membranes, damages DNA and proteins, and inhibits essential enzymes.

Biological functions

DisinfectionOxidationAntimicrobial activity

Disease associations

Infection

Safety considerations

InstabilityDecomposition at low pH or high temperaturesPotential for irritation at high concentrations

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