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The hypothalamo-olfactory pathway refers to the bidirectional neural communication between the olfactory system and the hypothalamus. It involves direct anatomical connections and functional modulation through neurotransmitters and neuropeptides. The pathway plays a role in homeostasis, feeding, arousal, and endocrine functions by integrating olfactory information with internal metabolic state and influencing olfactory processing via hypothalamic activity.
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