Hypoxanthine phosphoribosyltransferase 1 pseudogene 2 (HPRT1P2)

Hypoxanthine phosphoribosyltransferase 1 pseudogene 2 (HPRT1P2) is an intronless processed pseudogene found on human chromosome 5 that shares high sequence similarity with the functional HPRT1 gene, but lacks the capacity to produce a functional protein[2][4][1]. Pseudogenes are nonfunctional segments of DNA resembling protein-coding genes, often arising by gene duplication or retrotransposition. They typically lack regulatory sequences and accumulate disabling mutations such as frameshifts or premature stop codons[4]. While some pseudogenes have regulatory roles at the RNA level, no specific biological or disease functions are attributed to HPRT1P2, nor does it interact with drugs or serve as a therapeutic target[4][2][1].

Other names

HPRTP2HPRT1P2

None (not a drug target; mechanisms are not applicable)