IBR domain containing 3 pseudogene (ENSG00000231136)

The IBR domain containing 3 pseudogene (ENSG00000231136) is a genomic DNA segment containing sequence similarity to genes encoding the IBR (In Between Ring fingers) domain—a motif usually found in proteins involved in ubiquitin ligase complex formation and protein quality control[2]. As a pseudogene, it is not generally transcribed or translated into a functional protein, and possesses mutations or deletions that disable its canonical protein-coding function. Some pseudogenes have regulatory roles or participate in RNA-based regulation, but the specific biological significance of IBR domain containing 3 pseudogene has not been characterized and it is not considered a therapeutic target[1][3][7]. This entry is not a receptor, enzyme, transporter, or conventional drug target, and should not be included in structured drug-target databases unless specifically cataloging pseudogene elements or regulatory noncoding RNAs. If searching for a true target in the IBR domain family, refer instead to functional genes such as Ring Finger Protein 19A (RNF19A) or Ring Finger Protein 144B (RNF144B)[4][6].