IFNAR2-IL10RB readthrough protein (IFNAR2-IL10RB)

IFNAR2-IL10RB readthrough is a naturally occurring transcript generated by splicing between the neighboring IFNAR2 and IL10RB genes on chromosome 21, resulting in a chimeric mRNA that encodes a fusion protein combining parts of both gene products. While IFNAR2 and IL10RB encode receptors critical for antiviral and immune signaling, the function, tissue expression, and clinical significance of the IFNAR2-IL10RB readthrough are not established. It is cataloged in gene/protein databases as a protein-coding gene, but there is no evidence that this readthrough protein exists or functions as a discrete, druggable receptor in vivo. Disease associations cited for this locus pertain to the parental genes, and the readthrough product itself is not a standard target in pharmacological research.

Other names

IFNAR2-IL10RBIFNAR2-IL10RB readthroughIFNAR2-IL10RB protein

None known or established for the readthrough protein.