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The Ig kappa chain V-I region Lay pseudogene (ENSG00000277852) is a non-functional pseudogene classified within the immunoglobulin kappa light chain variable region gene family. Pseudogenes such as this arise through accumulated mutations that prevent them from encoding functional protein products and are a common feature in the immunoglobulin gene loci, reflecting the evolutionary complexity and diversification of antibody genes. As a pseudogene, it does not produce a protein, does not participate in immune response, and is not considered a therapeutic, diagnostic, or druggable target[1][2][9][10].
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